Compile Data Set for Download or QSAR
Found 41 of ic50 data for complexid = 50000178
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170589((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481206(CHEMBL595311)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170586((3S)-3-{[(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50140089(CHEMBL437423 | GCCSHPACAGNNQHIC*)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481212(CHEMBL609593)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50445323(CHEMBL3104236)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z171MPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170592(CHEMBL411146)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50081733(3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481211(CHEMBL595312)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170584(CHEMBL411145)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 3-5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481207(CHEMBL595286)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50140087(CHEMBL265198 | GCCSNPVCHLEHSNLC*)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 0.5-8 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481208(CHEMBL594330)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170600((3S)-3-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481210(CHEMBL609594)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50083075(3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50083057(3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line Sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)copy SMILES
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49T6PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170588(CHEMBL451252)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50445327(CHEMBL3104240)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of alpha3beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z171MPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human alpha3beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z171MPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170603((3S)-3-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50481209(CHEMBL595047)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DN8PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50445325(CHEMBL3104238)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z171MPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50083076(6-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50083069(6-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 217nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50601894(CHEMBL5196098)copy SMILES
Affinity DataIC50: 219nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49T6PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170594((16R)-9,33-dihydroxy-10,25-dimethoxy-15,15,30-trim...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50369323(MECAMYLAMINE)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50083079(3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 854nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GX6
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50061562((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170594((16R)-9,33-dihydroxy-10,25-dimethoxy-15,15,30-trim...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50567433(CHEMBL4869892)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN77P3PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)copy SMILES
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3Q8VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SG3PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SG3PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50567435(CHEMBL4872191)copy SMILES
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN77P3PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50061562((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed